Its difficult to generalise with pheros - You need to find what works for each one with you,
For MX297 - Its a great social/charasmatic/engaging mix but I’d suggest you don’t go higher than two sprays unless you actually want to be friendzoned. The exception would be if you were very physically imposing/unapproachable or had a very high natural none signature and needed to soften your impact considerably.
For IH - Yes, you probably could. I often find 3-4 sprays good to initiate deep, close conversation. Its not exactly first date stuff (unless combined with IS) but on subsequent dates, it really helps you get close.
Ammo - Have you found your sweet spot?
Because the none-based pheros are trickiest here, for some, three sprays or more might well be fine but others might find it too much when combined with their own natural signature.