# PDD (pregna-4,20-diene-3,6-dione): a vomeropherin that primarily affects men **URL:** \ **Category:** Men's Pheromone Advice & Field Reports\ **Created:** [June 16, 2007, 6:07am UTC](https://pheromonetalk.com/t/pdd-pregna-4-20-diene-3-6-dione-a-vomeropherin-that-primarily-affects-men/4151 "2007-06-16T06:07:22Z")\ **Posts on this page:** 14\ **Page:** 1
**Author:** ![MarkL](https://sea2.discourse-cdn.com/flex016/user_avatar/pheromonetalk.com/markl/32/825_2.png) [@MarkL](https://pheromonetalk.com/u/MarkL)\ **Post date:** [June 16, 2007, 6:07am UTC](https://pheromonetalk.com/t/pdd-pregna-4-20-diene-3-6-dione-a-vomeropherin-that-primarily-affects-men/4151/1 "2007-06-16T06:07:22Z")
No, not pervasive developmental delay. _Pregna-4,20-diene-3,6-dione_ Scientists have begun using naturally occurring human [pheromones](https://a314.com/shop/) to serve as models for designing novel synthetic compounds known as vomeropherins. Pregna-4,20-diene-3,6-dione is the first of these pheromones in this class. Unlike androstenoids, this compound was discovered to primarily affect the male gender. This is the first compound discovered to have an effect on the male VMO. There is an augmentation of the alpha brain waves upon exposure to pregnadiendione. Subjects reportedly experienced a decrease in both cardiac frequency and respiration as they became more relaxed. There was a decrease in both testosterone and LH produced, while follicle stimulating hormone (FSH) production increased. It is quite likely that this compound will be employed in the perfume industry. I’m not aware of PDD in the Androtics lineup. Can anyone point me to a source? ---
**Author:** ![Smudge](https://avatars.discourse-cdn.com/v4/letter/s/47e85d/32.png) [@Smudge](https://pheromonetalk.com/u/Smudge)\ **Post date:** [June 16, 2007, 7:30am UTC](https://pheromonetalk.com/t/pdd-pregna-4-20-diene-3-6-dione-a-vomeropherin-that-primarily-affects-men/4151/2 "2007-06-16T07:30:41Z")
Haven’t come across it here. LS does carry Master & Mistress. Both of them contain vomeropherins as well as other things that are not so common. Have tried Master personally when it first came out. It was sweet and powdery in smell, but didn’t do a thing for me in terms of self-awareness or otherwise. ---
**Author:** ![ProtoJay](https://avatars.discourse-cdn.com/v4/letter/p/7feea3/32.png) [@ProtoJay](https://pheromonetalk.com/u/ProtoJay)\ **Post date:** [June 16, 2007, 10:08am UTC](https://pheromonetalk.com/t/pdd-pregna-4-20-diene-3-6-dione-a-vomeropherin-that-primarily-affects-men/4151/3 "2007-06-16T10:08:44Z")
> [@MarkL](#): > > No, not pervasive developmental delay. > > _Pregna-4,20-diene-3,6-dione_Scientists have begun using naturally occurring human pheromones to serve as models for designing novel synthetic compounds known as vomeropherins. > > Pregna-4,20-diene-3,6-dione is the first of these pheromones in this class. Unlike androstenoids, this compound was discovered to primarily affect the male gender. > > This is the first compound discovered to have an effect on the male VMO. There is an augmentation of the alpha brain waves upon exposure to pregnadiendione. Subjects reportedly experienced a decrease in both cardiac frequency and respiration as they became more relaxed. There was a decrease in both testosterone and LH produced, while follicle stimulating hormone (FSH) production increased. It is quite likely that this compound will be employed in the perfume industry. > > I’m not aware of PDD in the Androtics lineup. Can anyone point me to a source? May I ask why you would want to acquire this? To me, it seems more useful to females as it is discovered to affect primarily the male gender. ---
**Author:** ![MarkL](https://sea2.discourse-cdn.com/flex016/user_avatar/pheromonetalk.com/markl/32/825_2.png) [@MarkL](https://pheromonetalk.com/u/MarkL)\ **Post date:** [June 16, 2007, 2:09pm UTC](https://pheromonetalk.com/t/pdd-pregna-4-20-diene-3-6-dione-a-vomeropherin-that-primarily-affects-men/4151/4 "2007-06-16T14:09:18Z")
Well, since you ask so politely – I’ve never discriminated (neither in the derogatory nor in the affirmative action senses) between females and males. My local bar is an “all lifestyles” venue and on any given night half of the men and women are looking for someone of the same sex. By not courting such limits, I effectively double my chances. It’s probably better to think of me as a reasonably well-lettered individual who understands romance and has a little game but whose chief asset is having the sexual inhibitions of a carnival roadie – a little less pop than “love the one you’re with.” In a more serious vein: self-effect is an important dynamic, and so is the relationship (perceived and otherwise) with other males even when one’s primary interest is a female. And, I’m interested in just playing with PDD to see how I and others react. Reading the reports of studies isn’t as satisfying to me as hands-on field testing. And last, I’m learning to make perfumes. Since you asked. Perhaps more than you wanted to know, heh! ---
**Author:** ![sweetsense](https://avatars.discourse-cdn.com/v4/letter/s/258eb7/32.png) [@sweetsense](https://pheromonetalk.com/u/sweetsense)\ **Post date:** [June 16, 2007, 2:21pm UTC](https://pheromonetalk.com/t/pdd-pregna-4-20-diene-3-6-dione-a-vomeropherin-that-primarily-affects-men/4151/5 "2007-06-16T14:21:29Z")
I really don’t want anything reducing my testosterone level ---
**Author:** ![MarkL](https://sea2.discourse-cdn.com/flex016/user_avatar/pheromonetalk.com/markl/32/825_2.png) [@MarkL](https://pheromonetalk.com/u/MarkL)\ **Post date:** [June 16, 2007, 2:54pm UTC](https://pheromonetalk.com/t/pdd-pregna-4-20-diene-3-6-dione-a-vomeropherin-that-primarily-affects-men/4151/6 "2007-06-16T14:54:52Z")
> [@sweetsense](#): > > I really don’t want anything reducing my testosterone level Don’t get any older. Don’t get married. Avoid holding infants … or even baby dolls … at all costs. [Harvard Gazette: Marriage lowers testosterone](http://www.hno.harvard.edu/gazette/2002/09.19/01-testosterone.html) It seems likely that you should avoid licorice, soy, and never let anyone convince you to go on a low-fat diet. ---
**Author:** ![tacitus](https://avatars.discourse-cdn.com/v4/letter/t/6a8cbe/32.png) [@tacitus](https://pheromonetalk.com/u/tacitus)\ **Post date:** [June 16, 2007, 2:59pm UTC](https://pheromonetalk.com/t/pdd-pregna-4-20-diene-3-6-dione-a-vomeropherin-that-primarily-affects-men/4151/7 "2007-06-16T14:59:57Z")
🆒 Received my emwave HRV monitor (heart rate variability) via USPS today… this should be instructive… a new level of biofeedback that picks up on subtle changes in heart pattern… supposedly this is a core level indicator of body-mind connection, down at the level of the autonomic (or insect-brain… btw… the older model of the triune, or three stage brain should be replaced with a 4 stage, insect—reptilian—mamallian—hominid model, because we are finding, more and more, that the most ancient brain dates back to the pre-reptile stage, the cambrian era, and bugs, for all their lack of subtlety, have outsurvived everything else, so I would neve accuse a bug of being dumb in a survial race…) 🙄 🙄 … Which leaves us where ? 😕 One suspects we have danced around this topic of the quad-level brain because it is too damn existentially embarrassing… however a close look at the sympathetic chain or the parasympathetic mesh does suggest that we are built on much the same neurological platform as the… TA DA !!!.. cockroach… 🆒 Sooooo… what better thing to probe, as far as chemo-reception and bugself-ness than bugthink… which HRV seems to be converging on… ---
**Author:** ![PheroQuirk](https://avatars.discourse-cdn.com/v4/letter/p/9e8a1a/32.png) [@PheroQuirk](https://pheromonetalk.com/u/PheroQuirk)\ **Post date:** [June 16, 2007, 3:39pm UTC](https://pheromonetalk.com/t/pdd-pregna-4-20-diene-3-6-dione-a-vomeropherin-that-primarily-affects-men/4151/8 "2007-06-16T15:39:49Z")
> [@tacitus](#): > > 🆒 Received my emwave HRV monitor (heart rate variability) via USPS today… this should be instructive… a new level of biofeedback that picks up on subtle changes in heart pattern… supposedly this is a core level indicator of body-mind connection, down at the level of the autonomic (or insect-brain… btw… the older model of the triune, or three stage brain should be replaced with a 4 stage, insect—reptilian—mamallian—hominid model, because we are finding, more and more, that the most ancient brain dates back to the pre-reptile stage, the cambrian era, and bugs, for all their lack of subtlety, have outsurvived everything else, so I would neve accuse a bug of being dumb in a survial race…) 🙄 🙄 … > > Which leaves us where ? 😕 > > One suspects we have danced around this topic of the quad-level brain because it is too damn existentially embarrassing… however a close look at the sympathetic chain or the parasympathetic mesh does suggest that we are built on much the same neurological platform as the… TA DA !!!.. cockroach… 🆒 > > Sooooo… what better thing to probe, as far as chemo-reception and bugself-ness than bugthink… which HRV seems to be converging on… how much does a good hrv monitor cost? any suggestions on sources? how long does a sample is required to assess hrv? is this something portable you can whip out when it would be interesting to check hrv status, or are there lots of pads to attach? ---
**Author:** ![MarkL](https://sea2.discourse-cdn.com/flex016/user_avatar/pheromonetalk.com/markl/32/825_2.png) [@MarkL](https://pheromonetalk.com/u/MarkL)\ **Post date:** [June 18, 2007, 5:36am UTC](https://pheromonetalk.com/t/pdd-pregna-4-20-diene-3-6-dione-a-vomeropherin-that-primarily-affects-men/4151/9 "2007-06-18T05:36:25Z")
Call the marshalls, there’s a hijacking in progress! ---
**Author:** ![sweetsense](https://avatars.discourse-cdn.com/v4/letter/s/258eb7/32.png) [@sweetsense](https://pheromonetalk.com/u/sweetsense)\ **Post date:** [June 18, 2007, 1:32pm UTC](https://pheromonetalk.com/t/pdd-pregna-4-20-diene-3-6-dione-a-vomeropherin-that-primarily-affects-men/4151/10 "2007-06-18T13:32:12Z")
Sounds like PPD is secreated by women when they feel comfortable in a relationship and want their mate to reduce his desire to prowl for other mates. ---
**Author:** ![PheroQuirk](https://avatars.discourse-cdn.com/v4/letter/p/9e8a1a/32.png) [@PheroQuirk](https://pheromonetalk.com/u/PheroQuirk)\ **Post date:** [June 19, 2007, 5:25pm UTC](https://pheromonetalk.com/t/pdd-pregna-4-20-diene-3-6-dione-a-vomeropherin-that-primarily-affects-men/4151/11 "2007-06-19T17:25:30Z")
> [@MarkL](#): > > Call the marshalls, there’s a hijacking in progress! so… any thoughts? where do we get hold of PDD? ---
**Author:** ![Socrates](https://avatars.discourse-cdn.com/v4/letter/s/3bc359/32.png) [@Socrates](https://pheromonetalk.com/u/Socrates)\ **Post date:** [June 20, 2007, 9:13am UTC](https://pheromonetalk.com/t/pdd-pregna-4-20-diene-3-6-dione-a-vomeropherin-that-primarily-affects-men/4151/12 "2007-06-20T09:13:21Z")
Pregna-4,20-diene-3,6-dione (PDD) might already be in the putatives… if not we can make a request I guess but don’t expect them to reveal which putative it is (which is fine by me)… **PDD may primarily effect the male VNO but we know that a molecule like Estratetraenol which primarily affects the male VNO, still works fine in real life as a [pheromone](https://a314.com/shop/) on women.** For PDD “There was a decrease in both testosterone and LH produced, while follicle stimulating hormone (FSH) production increased”. While the decrease in testosterone and LH does not take my fancy, in men, FSH enhances the production of [androgen-binding protein](http://en.wikipedia.org/wiki/Androgen-binding_protein) by the [Sertoli cells](http://en.wikipedia.org/wiki/Sertoli_cell) of the [testes](http://en.wikipedia.org/wiki/Testes) and is critical for [spermatogenesis](http://en.wikipedia.org/wiki/Spermatogenesis). (source: [Follicle-stimulating hormone - Wikipedia, the free encyclopedia](http://en.wikipedia.org/wiki/Follicle-stimulating_hormone)). I wonder if it will have the same (or any) effects on hormones in women? Visionary ---
**Author:** ![MarkL](https://sea2.discourse-cdn.com/flex016/user_avatar/pheromonetalk.com/markl/32/825_2.png) [@MarkL](https://pheromonetalk.com/u/MarkL)\ **Post date:** [June 25, 2007, 2:25pm UTC](https://pheromonetalk.com/t/pdd-pregna-4-20-diene-3-6-dione-a-vomeropherin-that-primarily-affects-men/4151/13 "2007-06-25T14:25:54Z")
> [@PheroQuirk](#): > > so… any thoughts? where do we get hold of PDD? > [@Socrates](#): > > Pregna-4,20-diene-3,6-dione (PDD) might already be in the putatives… if not we can make a request I guess but don’t expect them to reveal which putative it is (which is fine by me)… > > **PDD may primarily effect the male VNO but we know that a molecule like Estratetraenol which primarily affects the male VNO, still works fine in real life as a pheromone on women.** > … > > I wonder if it will have the same (or any) effects on hormones in women? Meh. I’m still trying to find a source, just as helpless now as when I started this thread, hah! Because, like Visionary, I wonder about PDD’s effects … and my program of choice is to experiment directly. Oh Princess Jasmin! If Androtics has some PDD floating around somewhere … how about offering a chemset supply? (That won’t compromise information on any MXnnn or Pnn or even TA? items already in play.) ---
**Author:** ![MarkL](https://sea2.discourse-cdn.com/flex016/user_avatar/pheromonetalk.com/markl/32/825_2.png) [@MarkL](https://pheromonetalk.com/u/MarkL)\ **Post date:** [June 27, 2007, 11:14pm UTC](https://pheromonetalk.com/t/pdd-pregna-4-20-diene-3-6-dione-a-vomeropherin-that-primarily-affects-men/4151/14 "2007-06-27T23:14:36Z")
_bump_ Anyone?