# Pheromone dosage response curves

**URL:** <https://pheromonetalk.com/t/pheromone-dosage-response-curves/100>\
**Category:** Pheromone Theory & Molecules\
**Created:** [January 12, 2006, 3:03pm UTC](https://pheromonetalk.com/t/pheromone-dosage-response-curves/100 "2006-01-12T15:03:25Z")\
**Posts on this page:** 1\
**Showing post:** 13

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**Author:** ![jumbolaya](https://avatars.discourse-cdn.com/v4/letter/j/2bfe46/32.png) [@jumbolaya](https://pheromonetalk.com/u/jumbolaya)\
**Post date:** [March 3, 2008, 4:23am UTC](https://pheromonetalk.com/t/pheromone-dosage-response-curves/100/13 "2008-03-03T04:23:04Z")

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> [@MHarris](#):
>
> Right, when using super high amounts, sometimes you don’t get the “character” of a pheromone, as much as you sometimes seem to get something else entirely.
> 
> I think it’s because when you’re overexposed to some pheromones, it’ll “drown out” the others.
> 
> Let me figure out how to explain this…
> 
> We still don’t know what receptors (keyholes) pheromones are fitting into, but normal body chemistry works the same way. You can block some of the body’s chemicals from having an effect by flooding the body with certain agonists (keys).
> 
> Bodybuilders do this by taking supplments that “bind” (fit into) the estrogen receptors (keyholes), blocking real estrogens from fitting in and turning they key. That’s how they prevent themselves from getting too fat, or taking on female characteristics.
> 
> Blocking action can be as important as actually “doing something” on their own.
> 
> So there’s not only the effect a certain chemical has, there’s the effect is has when it blocks other chemicals from doing their job. It appears that some pheromones do this at heavy concentration.
> 
> I’ve also seen some pheromones take on a different character when used in neglible amounts.
> 
> So there’s a “sweet spot” when you get the normal, preferred and often well known character of pheromones. i.e., androstenol being “friendly”.
> 
> Then there’s a more sublt and sometimes different effect when they’re used in what would SEEM like negligible amounts.
> 
> Finally, there’s a seemingly different chracter entirely when used in high “overdose” amounts.
> 
> It’s just like saying there’s lots of shades of personality… there’s shades of chemical personalities, too.
> 
> You need a minimal amount of vitamins to not get scurvy, for instance, but you can often use large amounts to extend your life, or give you more energy, or what have you. Different character emerges at different dosages.

I have a question regarding adverse effects. People have talked about “self effects” of pheromones, OD-ing, and head rushes. Also, there was a post/article about how nursing mothers use (natural) pheromones to bond with their newborns: [Using Pheromones for Attraction and Bonding](https://pheromonetalk.com/t/using-pheromones-for-attraction-and-bonding/836)

Are there potential negative, long-term side effects? Over time, one will become used to the pheromone signature and might have to up the dose or mix it up a bit to get the same effects, but are there any serious ones?? After readings the posts (my package comes in the mail tomorrow!) it seems pheromones are very potent and very serious stuff- very drug-like. Just wondering if you (or anyone) knows anything about long-term effects (eg. like messing up neuropathways/receptors, any effects while breast feeding, etc.). Thanks!

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