# Pheromones for premenstrual syndrome: discussing the New Scientist nasal spray report **URL:** \ **Category:** Pheromone Theory & Molecules\ **Created:** [January 21, 2008, 5:20am UTC](https://pheromonetalk.com/t/pheromones-for-premenstrual-syndrome-discussing-the-new-scientist-nasal-spray-report/8492 "2008-01-21T05:20:40Z")\ **Posts on this page:** 7\ **Page:** 1
**Author:** ![Mohammad\_Shah](https://sea2.discourse-cdn.com/flex016/user_avatar/pheromonetalk.com/mohammad_shah/32/873_2.png) [@Mohammad\_Shah](https://pheromonetalk.com/u/Mohammad_Shah)\ **Post date:** [January 21, 2008, 5:20am UTC](https://pheromonetalk.com/t/pheromones-for-premenstrual-syndrome-discussing-the-new-scientist-nasal-spray-report/8492/1 "2008-01-21T05:20:40Z")
(From New Scientist Print Edition. Catherine Zandonella, San Francisco) Women suffering from premenstrual syndrome may soon get instant relief from a mix of [pheromones](https://pheromonelabs.com/shop/), the airborne chemical messengers best known for their role in animal mating behaviour. They’ll get the pheromones in a simple nasal spray. The spray’s makers claim it will free women from the irritability, depression and other symptoms of premenstrual syndrome (PMS) and the more severe premenstrual dysphoric disorder (PMDD). Early tests on 20 women show that the spray eased both mood disorders and physical symptoms like breast pain. PMS affects up to 40 per cent of women of childbearing age. Many researchers now think the condition is sparked by fluctuating hormones affecting brain activity. As a treatment doctors often prescribe mood-altering drugs such as Prozac, which works by elevating serotonin levels in the brain. Human pheromones are powerful mediators of sexual attraction, anxiety and hormone-related disorders, says David Berliner, one of the founders of Pherin Pharmaceuticals of Mountain View, California, the company developing the spray. **Direct connection** For years, few researchers believed human pheromones existed, but over the past decade Berliner and others have shown that these chemicals, exuded from human skin, can induce calmness in the opposite sex. The chemicals are detected by a specialised organ in the nose, called the vomeronasal organ or VNO. To target premenstrual syndrome, Pherin has developed a pheromone-like compound or “vomeropherin” known as PH80. With each inhalation, PH80 binds to receptors in the VNO. Nerve cells then speed the message to the hypothalamus, the part of the brain dedicated to maintaining homeostasis, the body’s chemical balance. Because the vomeropherin has a direct line to the brain, relief is immediate. The effect lasts 2 to 4 hours, says Berliner. Pherin is now setting up full clinical trials of the spray. “It’s an intriguing and novel approach,” says Bruce Kessel, a specialist in PMS at the University of Hawaii. Functional MRI scans show that a whiff of PH80 stimulates a region of the hypothalamus thought to affect PMS. The hypothalamus is involved in both the central nervous system and the endocrine system, regulating sexual drive, anxiety, fear and appetite among other traits. Berliner’s team is now developing different vomeropherins which they hope will target these behaviours. ---
**Author:** ![TRDE59](https://sea2.discourse-cdn.com/flex016/user_avatar/pheromonetalk.com/trde59/32/412_2.png) [@TRDE59](https://pheromonetalk.com/u/TRDE59)\ **Post date:** [January 21, 2008, 7:05am UTC](https://pheromonetalk.com/t/pheromones-for-premenstrual-syndrome-discussing-the-new-scientist-nasal-spray-report/8492/2 "2008-01-21T07:05:36Z")
If Hillary Clinton gets elected president, we’re gonna need truckloads of this delivered to her every month… ---
**Author:** ![z414a4d](https://sea2.discourse-cdn.com/flex016/user_avatar/pheromonetalk.com/z414a4d/32/1299_2.png) [@z414a4d](https://pheromonetalk.com/u/z414a4d)\ **Post date:** [January 21, 2008, 3:55pm UTC](https://pheromonetalk.com/t/pheromones-for-premenstrual-syndrome-discussing-the-new-scientist-nasal-spray-report/8492/3 "2008-01-21T15:55:16Z")
> [@TRDE59](#): > > If Hillary Clinton gets elected president, we’re gonna need truckloads of this delivered to her every month… Very nice…Very nice… 🙂 ---
**Author:** ![moleculsedux](https://avatars.discourse-cdn.com/v4/letter/m/aca169/32.png) [@moleculsedux](https://pheromonetalk.com/u/moleculsedux)\ **Post date:** [June 1, 2008, 11:17am UTC](https://pheromonetalk.com/t/pheromones-for-premenstrual-syndrome-discussing-the-new-scientist-nasal-spray-report/8492/4 "2008-06-01T11:17:35Z")
[Instant Female Magic](https://a314.com/product/instant-female-magic/) seemed to eradicate my girlfriends PMS completely. ---
**Author:** ![bubblebob](https://sea2.discourse-cdn.com/flex016/user_avatar/pheromonetalk.com/bubblebob/32/2120_2.png) [@bubblebob](https://pheromonetalk.com/u/bubblebob)\ **Post date:** [June 1, 2008, 3:10pm UTC](https://pheromonetalk.com/t/pheromones-for-premenstrual-syndrome-discussing-the-new-scientist-nasal-spray-report/8492/5 "2008-06-01T15:10:26Z")
I wonder if vomeropherin might just be our well known Androstadienone known to do exactly the same??? ---
**Author:** ![Wolfy](https://sea2.discourse-cdn.com/flex016/user_avatar/pheromonetalk.com/wolfy/32/965_2.png) [@Wolfy](https://pheromonetalk.com/u/Wolfy)\ **Post date:** [June 4, 2008, 4:10am UTC](https://pheromonetalk.com/t/pheromones-for-premenstrual-syndrome-discussing-the-new-scientist-nasal-spray-report/8492/6 "2008-06-04T04:10:52Z")
> [@TRDE59](#): > > If Hillary Clinton gets elected president, we’re gonna need truckloads of this delivered to her every month… I thought she was to old for that problem… 😃 Isn’t [Instant Female Magic](https://a314.com/product/instant-female-magic/) bottled Bill Clinton? My Ex never seemed to have cramps when I was around, but she cried about them on the phone when I was away at school. From what I hear the best cure for PMS in women is a good orgasm. (from some friends who swore by it. As well as one who was on muscle relaxants one week a month for cramps. After she learned this fact she stole a back massager once a month, so she did not have to drug herself limp) That in mind, any concoution that helped get your female friend’s fire started should help. IFM, TUTH, or even Ammo all could help. ---
**Author:** ![Edx](https://avatars.discourse-cdn.com/v4/letter/e/4da419/32.png) [@Edx](https://pheromonetalk.com/u/Edx)\ **Post date:** [June 10, 2008, 7:14pm UTC](https://pheromonetalk.com/t/pheromones-for-premenstrual-syndrome-discussing-the-new-scientist-nasal-spray-report/8492/7 "2008-06-10T19:14:44Z")
This is really cool. Can I make an official request to have a section dealing with positive phermone reports in mainstream scientific press and journals?