# SSRI and pheromone production

**URL:** <https://pheromonetalk.com/t/ssri-and-pheromone-production/16819>\
**Category:** Pheromone Theory & Molecules\
**Created:** [August 3, 2008, 12:50pm UTC](https://pheromonetalk.com/t/ssri-and-pheromone-production/16819 "2008-08-03T12:50:34Z")\
**Posts on this page:** 13\
**Page:** 1

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**Author:** ![angelplus2012](https://avatars.discourse-cdn.com/v4/letter/a/a9adbd/32.png) [@angelplus2012](https://pheromonetalk.com/u/angelplus2012)\
**Post date:** [August 3, 2008, 12:50pm UTC](https://pheromonetalk.com/t/ssri-and-pheromone-production/16819/1 "2008-08-03T12:50:34Z")

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hi, i wonder anyone on Selective Serotonin Re-uptake Inhibitor (SSRI) medications experience any higher levels of pheromone production to yourself?  
since, i’m on ssri, i noticed that many things change around me, at workplace and at home and outdoors.  
at the workplace, the manager would start a long conversation with me about his family, his opinions, (which he never did before), colleagues smile more at me,and start conversations with me more. girls had longer eye contact with me, smile occasionally.  
my second opinion, is that ssri can lead to extra sweating to someone, and if that’s one of the way more [pheromones](https://a314.com/shop/) are produced in the armpits.  
anyone want to comment?

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**Author:** ![MeDieViL](https://sea2.discourse-cdn.com/flex016/user_avatar/pheromonetalk.com/medievil/32/1650_2.png) [@MeDieViL](https://pheromonetalk.com/u/MeDieViL)\
**Post date:** [August 3, 2008, 4:19pm UTC](https://pheromonetalk.com/t/ssri-and-pheromone-production/16819/2 "2008-08-03T16:19:02Z")

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i’m not sure about this one, but i have seen reports before of ppl being more friendly when taking herbs that work on gaba, i wouldnt be suprised if neurotransmitters could change [pheromone](https://a314.com/shop/) output

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**Author:** ![Kitten](https://sea2.discourse-cdn.com/flex016/user_avatar/pheromonetalk.com/kitten/32/1051_2.png) [@Kitten](https://pheromonetalk.com/u/Kitten)\
**Post date:** [August 3, 2008, 7:56pm UTC](https://pheromonetalk.com/t/ssri-and-pheromone-production/16819/3 "2008-08-03T19:56:44Z")

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Not to disagree with you, but I think neurotransmitters really can affect pheromone production, or at the very least they can _mimic_ pheromone effects.

Oh also, and most obviously, the fact that you no longer act depressed around people is going to have a huge effect on how they react to you. No one wants Eeyore to hang out with them. Happy shiny funny bunny on Prozac? Yes, please.

Best,  
Kitten

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**Author:** ![Daedelus76](https://avatars.discourse-cdn.com/v4/letter/d/eb8c5e/32.png) [@Daedelus76](https://pheromonetalk.com/u/Daedelus76)\
**Post date:** [August 4, 2008, 6:45am UTC](https://pheromonetalk.com/t/ssri-and-pheromone-production/16819/4 "2008-08-04T06:45:30Z")

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Maybe it is just your mood changing your perceptions and behavior. It depends on the reason you are taking SSRI’s, of course.

I’m not an expert, it’s been a long time since I read a book on neurobiology/neurochemistry, but the SSRI’s don’t really increase serotonin per se, they keep the serotonin from being re-absorbed. This causes serotonin to be available longer in the synapse. It also changes the sensitivity of serotonin receptors in the brain, and this in turn alters alot of different regions in the brain, some of which are involved with mood.

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**Author:** ![Phya](https://avatars.discourse-cdn.com/v4/letter/p/94ad74/32.png) [@Phya](https://pheromonetalk.com/u/Phya)\
**Post date:** [August 4, 2008, 7:32am UTC](https://pheromonetalk.com/t/ssri-and-pheromone-production/16819/5 "2008-08-04T07:32:14Z")

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> [@Daedelus76](#):
>
> Maybe it is just your mood changing your perceptions and behavior. It depends on the reason you are taking SSRI’s, of course.
> 
> I’m not an expert, it’s been a long time since I read a book on neurobiology/neurochemistry, but the SSRI’s don’t really increase serotonin per se, they keep the serotonin from being re-absorbed. This causes serotonin to be available longer in the synapse. It also changes the sensitivity of serotonin receptors in the brain, and this in turn alters alot of different regions in the brain, some of which are involved with mood.

That is correct. SSRI’s do not increase serotonin but actually bind to the serotonin reuptake receptors and prevents the serotonin from being broken down. This artificially ‘floods’ (or in this case ‘normalizes’) the synapses with serotonin.

FTC, MDMA achieves its effects in a similar way, except it uses the serotonin reuptake receptors in reverse, to flood the synapses with serotonin. Reportedly, if you take SSRIs, MDMA will not have the desired effect, since the SSRIs are already bound to the serotonin reuptake receptors. 🙂

One often overlooked side effect of MDMA is that with overuse, some of your serotonin receptors will shutdown in response to the continual ‘flooding’ of serotonin.

I think most likely, it has to do with your mood changes and the changes in your behavior. Even if there is some pheromonal change (which might be possible since it seems that pheromone signatures reflect our state of health to a degree), I would say that the majority of difference would be from the change in your behavior.

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**Author:** ![MeDieViL](https://sea2.discourse-cdn.com/flex016/user_avatar/pheromonetalk.com/medievil/32/1650_2.png) [@MeDieViL](https://pheromonetalk.com/u/MeDieViL)\
**Post date:** [August 4, 2008, 9:49am UTC](https://pheromonetalk.com/t/ssri-and-pheromone-production/16819/6 "2008-08-04T09:49:48Z")

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hehe anyone notices ppl seem more friendly on MDMA? i do

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**Author:** ![Phya](https://avatars.discourse-cdn.com/v4/letter/p/94ad74/32.png) [@Phya](https://pheromonetalk.com/u/Phya)\
**Post date:** [August 4, 2008, 7:26pm UTC](https://pheromonetalk.com/t/ssri-and-pheromone-production/16819/7 "2008-08-04T19:26:12Z")

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> [@MeDieViL](#):
>
> hehe anyone notices ppl seem more friendly on MDMA? i do

😃 Just a little. 🙄

Hence..the results being more likely a result of personal behavior change than a change in pheromone production.

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**Author:** ![MeDieViL](https://sea2.discourse-cdn.com/flex016/user_avatar/pheromonetalk.com/medievil/32/1650_2.png) [@MeDieViL](https://pheromonetalk.com/u/MeDieViL)\
**Post date:** [August 4, 2008, 9:13pm UTC](https://pheromonetalk.com/t/ssri-and-pheromone-production/16819/8 "2008-08-04T21:13:33Z")

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i dunno, one time a took a pill at school lol and this guy that never talks to me started talking to me when i walked passed him

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**Author:** ![fullmoonnow](https://sea2.discourse-cdn.com/flex016/user_avatar/pheromonetalk.com/fullmoonnow/32/1821_2.png) [@fullmoonnow](https://pheromonetalk.com/u/fullmoonnow)\
**Post date:** [August 22, 2008, 2:10am UTC](https://pheromonetalk.com/t/ssri-and-pheromone-production/16819/9 "2008-08-22T02:10:11Z")

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> [@MeDieViL](#):
>
> i’m not sure about this one, but i have seen reports before of ppl being more friendly when taking herbs that work on gaba, i wouldnt be suprised if neurotransmitters could change pheromone output

GABA herbs? hMM. Alcohol and benzodiazepines (same subclass as Valium) work to potentiate the GABA (major inhibitory) system - without going into details, the end result is in ‘lowering your inhibitions’.

So I suppose someone who was taking a substance that ‘lowered’ his inhibitions would be friendlier because he would be free from the constraints of prejudice / fear that often stop one from being as friendly as they like in this day and age.

Interestingly, the androstenols act on GABA as well. 🆒

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<div class="post-metadata">

**Author:** ![fullmoonnow](https://sea2.discourse-cdn.com/flex016/user_avatar/pheromonetalk.com/fullmoonnow/32/1821_2.png) [@fullmoonnow](https://pheromonetalk.com/u/fullmoonnow)\
**Post date:** [August 22, 2008, 2:18am UTC](https://pheromonetalk.com/t/ssri-and-pheromone-production/16819/10 "2008-08-22T02:18:25Z")

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For more info on the wonderful GABA, try clicking [here](http://thebrain.mcgill.ca/flash/d/d_04/d_04_m/d_04_m_peu/d_04_m_peu.html).

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<div class="post-metadata">

**Author:** ![MeDieViL](https://sea2.discourse-cdn.com/flex016/user_avatar/pheromonetalk.com/medievil/32/1650_2.png) [@MeDieViL](https://pheromonetalk.com/u/MeDieViL)\
**Post date:** [September 7, 2008, 11:12pm UTC](https://pheromonetalk.com/t/ssri-and-pheromone-production/16819/11 "2008-09-07T23:12:30Z")

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> [@fullmoonnow83](#):
>
> GABA herbs? hMM. Alcohol and benzodiazepines (same subclass as Valium) work to potentiate the GABA (major inhibitory) system - without going into details, the end result is in ‘lowering your inhibitions’.
> 
> So I suppose someone who was taking a substance that ‘lowered’ his inhibitions would be friendlier because he would be free from the constraints of prejudice / fear that often stop one from being as friendly as they like in this day and age.
> 
> Interestingly, the androstenols act on GABA as well. 🆒

talking about herbs like gotu kola and stuff, in lowering your inhibitions they are pretty useless

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<div class="post-metadata">

**Author:** ![MeDieViL](https://sea2.discourse-cdn.com/flex016/user_avatar/pheromonetalk.com/medievil/32/1650_2.png) [@MeDieViL](https://pheromonetalk.com/u/MeDieViL)\
**Post date:** [September 8, 2008, 11:41am UTC](https://pheromonetalk.com/t/ssri-and-pheromone-production/16819/12 "2008-09-08T11:41:33Z")

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> [@lolgain](#):
>
> do somebody can work it??

what?😕

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<div class="post-metadata">

**Author:** ![PheroQuirk](https://avatars.discourse-cdn.com/v4/letter/p/9e8a1a/32.png) [@PheroQuirk](https://pheromonetalk.com/u/PheroQuirk)\
**Post date:** [September 8, 2008, 9:23pm UTC](https://pheromonetalk.com/t/ssri-and-pheromone-production/16819/13 "2008-09-08T21:23:54Z")

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> [@angelplus2012](#):
>
> hi, i wonder anyone on Selective Serotonin Re-uptake Inhibitor (SSRI) medications experience any higher levels of pheromone production to yourself?  
> since, i’m on ssri, i noticed that many things change around me, at workplace and at home and outdoors.  
> at the workplace, the manager would start a long conversation with me about his family, his opinions, (which he never did before), colleagues smile more at me,and start conversations with me more. girls had longer eye contact with me, smile occasionally.  
> my second opinion, is that ssri can lead to extra sweating to someone, and if that’s one of the way more pheromones are produced in the armpits.  
> anyone want to comment?

people around you will pick up on your vibe and emotional state from facial expression, posture/body language, tonality, pheromone production and quite possibly the emf radiation from your heart. this can operate at a very subtle level, but the point is that the totality of how people feel, perceive and think when they are around you will be shaped by your mood.

since an important aspect of pheromone signature relates to dominance, the below might be interesting.

[Subordination and Defeat : An Evolutionary Approach to Mood Disorders and Their Therapy](http://www.biopsychiatry.com/depression/index.html)

In another chapter, the other co-editor, Sloman, perceptively notes that “The evolutionary theorist faces the challenge of having to explain why mood disorders, which are often maladaptive for the individual, have not been weeded out by natural selection and, moreover, continue to have a high prevalence” (p. 47). He goes on to show how the involuntary defeat strategy (IDS, as he abbreviates it), which was evolved for adaptive purposes, can become maladaptive for an individual human in today’s world.  
When it works properly, IDS limits the level of aggression that might occur between individuals, signals “no threat” to opponents and “don’t intervene” to cohorts, and puts the subordinated person in a “giving up” frame of mind. The IDS fails to accomplish these goals, however, when the defeated individual cannot effectively escape the conflict situation. When this happens, the result is often learned helplessness followed by chronic, self-reinforcing, and thereby pathological depression. Depressed people often seem to resort prematurely to an IDS, even when the conflict is simply imagined or expected. “Premature triggering of the IDS may be attributed to a history of having autocratic and punitive parents, physical abuse, or sexual abuse” (p. 58).
