# The best mones to pick for guys who want to remain a challenge? **URL:** \ **Category:** Men's Pheromone Advice & Field Reports\ **Created:** [September 12, 2013, 12:00pm UTC](https://pheromonetalk.com/t/the-best-mones-to-pick-for-guys-who-want-to-remain-a-challenge/60001 "2013-09-12T12:00:16Z")\ **Posts on this page:** 1\ **Showing post:** 70
**Author:** ![monesmadedoit](https://sea2.discourse-cdn.com/flex016/user_avatar/pheromonetalk.com/monesmadedoit/32/325_2.png) [@monesmadedoit](https://pheromonetalk.com/u/monesmadedoit)\ **Post date:** [October 1, 2013, 7:34pm UTC](https://pheromonetalk.com/t/the-best-mones-to-pick-for-guys-who-want-to-remain-a-challenge/60001/70 "2013-10-01T19:34:38Z")
> [@dsouza](#): > > I asked Steve about Estradiol and if you look at his FORUM on PheromonesXS website you’ll see he claims that no dangerous compounds or side effects can come from it.. He has already made the CLAIM in his response to his clientelle. Furthermore, he says it is supplied in such small amounts that it is virtually negligible and cannot cross the blood brain barrier. > > SEE HIS RESPONSE ON HIS FORUM. Some of the molecules in his _and other companies_’ products are suspected neurosteroids, like THDOC. They are also suspected pheromones. Their mechanism is _unknown_. They may act by allosteric modulation of neurotransmitters, affecting mood by unknown paths in the central nervous system. Thus, P75, P102, TAF, etc. can cause neurotransmitter depletion, headache, agitation, insomnia, etc. in certain persons. They may alter endocrine feedback loops, shifting homeostatic balance. This is why females are highly prone to eating disorders but men are not. It is wildly more complex than I can begin to state here. The blood-brain barrier isn’t necessarily a factor as much as alteration of _CNS function_ by unknown means. Hormone levels could (it depends) be altered by “pushing” endocrine feedback loops in a certain direction. We can’t cure eating disorders, etc., because we just don’t know how it works. **The prenatal migration of GnRH neurosecretory neurons allow [human pheromones](https://pheromonelabs.com/) to effect GnRH pulsatility, which modulates the concurrent maturation of the neuroendocrine, reproductive, and central nervous systems, thus influencing the development of human reproductive sexual behavior and other behavior.** > [@question: pheromone biosynthesis pathways](https://pheromonetalk.com/t/question-pheromone-biosynthesis-pathways/31828): > > Warning: Newbie questions here. I’m wondering if there is available a diagram that maps out how the body synthesizes various [pheromones](https://pheromonelabs.com/shop/). Specifically, something that shows things like “testosterone breaks down in the body into this, and this is excreted onto the skin, where this bacteria changes it into this”, etc… I’m interested in this for two reasons. First, it might give clues as to why certain pheromones have certain effects. For example, a pheromone that is produced by a process that … --- _[View the full topic](https://pheromonetalk.com/t/the-best-mones-to-pick-for-guys-who-want-to-remain-a-challenge/60001)._