Let me clarilfy. In the search for what MEO EST is some experienced members thought it possible it was Equilin which is not humanly produced. This was all just speculation and it has not been confirmed or proven that MEO-EST is in fact Equilin. Androtics has said they deal with only human pheromones and musks so its not likely to be Equilin.
Here is the post that we discussed it in.
Keep in mind it was only a discussion and not a indication as to what it exactly.
In most cases the irritation is from the alcohol. Copulins are a exception due to the acidity. However most copulin products do not effect the skin either unless you have a old beta bottle which was extremely strong and undiluted.
Tisha