You really have to be careful with P83. It’s definitely something you can’t use in all environments, and must be buffered well. It’s like injecting the Id part of the psyche of the people around you with steroids, and having it dominate the superego. Which results in stronger instinctive urges, sex, aggression, and other primary processes. The higher dose you use, the more repressed your moral compass insisting on socially acceptable behavior becomes. This can also result in strong headaches if in high doses.
EDIT: Unfortunately I have not yet had a chance to test out P86, so I’d have to hold off on any thought on it.