Yes with anone its very real but it doesn’t happen as easy as some people tend to think. It takes weeks and weeks of using anone and not being hygienic enough. Water will wash some away and diffusion will take care of some.
Build up OD is more for those who keep applying frequently between applications. You can do that with some mones but not with anone. It also is harder to get out of your cloths.
Its not something to be afraid of. Its something to be aware of. If suddenly your anone mixes start getting the opposite reaction then you usually see then build up is a very real possibility.
Tisha