IO is big for killing social anxiety. So is androstenone/androsterone. If all you want to do is hammer on opening sets, go heavy on IO and IS mixed. Can’t lose with that combo: it’s life of the party time. 3+ sprays of each, at 1:1 if you do 3 sprays. Apply IO to neck and IS to wrists/forearms. I suggest 4-5 each. If you go 4-5 each, then apply in a 3/2 pattern: 3 sprays IO to neck, remainder to arms; 3 sprays IS to arms, remainder to neck.
If you want to add some masculine/sexy, consider adding a couple sprays of IG and a spray or two of TUTH. This will change the mix drastically, though… you might want to try out both options and see which you prefer first.