So, I’ve been using P83 with Ammo, IS and IO and A314. A314 is usually my daily base of 1-3 drops. I add IS and IO to take off the serious edge a little. Also Ammo because the ladies love it. 
I used P83 with that combination because I loved the self-effect. It gives you this amazing feeling, like there is no care in this world. Eventually I’ve noticed that it can actually intensify negative and depressing feeling. It basically amplifies them, and can really make you miserable. So I’ve completely stopped using it for now. Has anyone experienced this before? Also it would make me too careless, so much that it would effect my decisions. Which can be bad too, and this is why I don’t think it should be used all the time.
P83 leads to reduced inhibitions. So, it makes sense that you might be feeling that sense of losing control. Women prefer a dominant man who is in control of his own actions. That builds trust and facilitates attraction. If you are feeling careless or prone to making bad decisions, by all means stop using it. And, in a social environment, refrain from drinking alcohol. At the end of the night, it’s the sober guy who gets the girl. 
I find it fascinating that anyone gets self effects off of anything to be honest. I have a few products I have dabbled in and so far nothing. I experience no effect at all on myself but see the effects on others when I know what I am looking for as documented in my journal. Is there a problem with my sniffer? I keep reading about how it makes people feel when they use stuff but for me, its just nice smelling, thats it.
No, nothing wrong with you - Self effects are highly variable beteen individuals and individual pheros. Some get not a lot, nothing at all or very strongly. Some also get them initially but get used to them in time - sometimes a very short time, again often depending on phero. This can also mean that in time, an effectife dose for self effects can become so high that it becomes counterproductive/OD for people around you, so ultimately its a self-defeating excercise.
I’m another who tends not to get much by self effects from many products but so long as they are delivering the goods around other people, all is good.
Does this mean that people who don’t get self-effects are also ‘immune’ or less responsive to the effects of pheros worn by others?
Response is always rather variable with people - Some give strong and obvious responses, others very subtle and some nothing at all. You always have to consider this.
True, but I was wondering if there’s any correlation between degree of responsiveness and self-effects. Seeing that you’ve never felt that much of a self-effect, would you be less responsive to a woman wearing pheros than me, for example?