I think a lot of people misunderstand this. You can overlap right away if you want to. It wont effect the mones adversely. If it did we wouldn’t be able to mix in bottles.
There is only one reason that we suggest waiting and that is when you are going to cover with a cologne because you dont like the smell of the mone mix on its own. Waiting for dry down prevents the underling scent from bleeding through and cover more effectively.
So its up to you 
The classic OD meaning the Ghost effect, no response, or overly cranky aggressiveness usually only applies to Anone products. You will need alot of A314 to get there because it doesn’t contain a lot of anone. However to much of anything can be bad or non productive. Ishine can cause headaches when over used due to the rapid fire of your neurotransmitters. IO can cause sleep disturbances. So those things could be considered OD effects but we tend to call them side effects. All mild side effects but worth noting.
Most people have a range for each product they use.
The low range of sprays cause subtle differences, these are when you first just begin to see behavior changes in people. The higher range will cause your less subtle more obvious hits. The mega dose as Jasmin likes to call it can do nothing or change the effect somewhat.
Take spaceland for instance. Its 50mcg of anol per spray. IO is also primarily anol but you get a slightly different type effect from them.
IO is friendly, makes people feel sociable and comfortable. Increase the urge to interact and talk more.
Spaceland puts you in a laid back fun party zone. Its sort of goofy and you feel like you have been drinking or your high. You can zone out a bit when using it. It loosens everything up. Coming down off of it is a bitch I will suddenly get very very tired but my mind is still running 100 miles a hour and I cant sleep. Still good shit though LOL
Similar but different…
I find with IH that is causes a feeling of closeness connection deep conversation. Low doses make you the best friend and confidant. Your higher range is similar but more intimate, Mega dose and I can talk your pin number out of you and make you tell me every single embarrassing thing about yourself. The next day people can seem a bit shell shocked by some of the things they blurt out to you. The awkwardness is the side effect mostly for people your not normally close to who spill there guts. For those close they take it different because they already established a re-pore with you.
Finding your normal low and high range is fine, Of course do this carefully with anone products. Going into mega dosing is interesting and can tell you alot about a mix but its not practical to do all the time and it is sort of a waste of products. To much of a good thing is not always better.
Now with the putatives you really should mega dose a few times but these are in testing and you may not see any effect till you hit a high dose. This tells the research group that a particular molecule needs to be used in higher dosages in a mix to see the effects of it.
Tisha