Hi Juliedude, I think Astrea answered your question on whether you need to use perfume over it. On how to use them, read on! We need to find our “Sweet Spot” for each pheromones. This is not the area of where we should spray the pheromones (that was my first thought when i read the term!). It is finding out how many sprays work best for us. Too little and we see no effect, too much and people will get negative reactions. Here’s a great post on how to find our Sweet Spot : How to find your sweet spot… - PheroTalk Pheromone Research Forum Then we also need to find out what’s the best application method. Should we spray over our hair? Use them like a traditional perfume and dab on our wrists and/or neck area? Here’s a post by the amazing Tisha on various application methods (depending on whether and kind of phero u are testing out) Tisha's application tips Hope this helps =)) I’m so happy to be able to help as the girls here made me feel so welcome!