I have my guesses, but I my ultimate answer would be “I don’t know yet”, because the dataset I have to work with is too small.
While I ask everyone I come into contact with what their bloodtype is, most don’t know. To expect them to know if they’re Rh positive or negative is like expecting the Statue of Liberty to talk. 
This should all change with this forum, and the blood type indicator in the profile.
Now, opinion wise, I think secretor status (which refers to blood type related antigens appearing in bodily fluids other than blood) will come into play much more signficantly than the presence of Rh (which is a single antigen). There are some significant differences in optimal diets of secretors and non-secretors of the same blood type.
I think whenever food reactions change across a subgroup, that shows a distinct difference in genetics, metabolism and immune response. Of course, when genetics change, so do inherent pheromonal profiles.
Pheromones allow you, in part, to sniff out facets of genetics, immune response, and metabolism of another human being.
Let’s watch and learn… let’s make sure everyone enters their blood type info into their profile, so we can begin to see connections between what works, how, and for whom of which blood type.
I’ll add secretor status soon. About 80% of the population are secretors.