Hi therapygirl 
You may find this article interesting.
You should also do a search on Instant Female Magic/androstadienone if you haven’t already. 
Well, there have been reported depressive effects in men. Some men, not all, and not many neg reports. That’s why we tell them to spray it to the back of their heads, just in case. The mens version of Instant Female Magic has a buffer to counter some of the reported depressive effects. They’ll still be effected but a bit less than spraying it right up front. Most guys like it for taming “the beast” at that time of the month. Also works for grumpypusses in general. The other neg, if you consider it one, is some women have reported becoming tired and/or sleepy when wearing it. I can feel the effects of Instant Female Magic whether I’m wearing it or Wolf is.
Hope this helps,
Bella