https://pheromonetalk.com/t/the-blood-type-pheromone-connection/16/66
Effects have even been seen with as little as 100 picograms as I mentioned there. Our bodies have nanogram amounts and we are using enhanced diffusion to deliver it so keep trying lower and let me know the lowest dose that has the same effects since you happen to be playing with it now. I had suggested 500 nanograms next, I have tried only down to 1mcg which worked the same as 4. I have been curious if at any amount those like you that are sensitive might no longer get the negative effects which may allow a company like androtics to use it again. It has been tried to combine it with things like Dhea, Dheas etc that lift mood but eventually most everyone still got depression effects after awhile. It also reduces the crush effects on the woman doing that.
https://pdfs.semanticscholar.org/2e31/ac2b3d0331a4e509f1fbde9462f5bb5d33aa.pdf
This and one other study I have mentions that androstadienone exposure makes a person be able to detect it at lower and lower levels, with the scent turning from pleasant to negative. A change in the effects may go along with that to not work as well.
https://pheromonetalk.com/t/hedione-increases-one-night-stands-and-sex-behavior-in-women/67685
Hedione does have the sexual turn on effect, but in there I also link studies that it hits the brain like androstadienone so it also has the social and buffering properties.Please let me know if used solo you get any depression effect but I think it doesnt but I dont have A1 depression.
So when using the mix will be dependent on if you have higher natural pheromone levels then you would use more hedione, but someone with lower levels would want more androstenone and less hedione since it buffers. Copulins increase lutenizing hormone which increase testosterone leading to sex drive increase in both sexes. When a women is about to ovulate her lutenizing hormone levels are at the highest when she is most sexual. This may be the same thing that hedione does, triggering GnRh to release LH to increase testosterone… Try it without the copulins as you may get identical results other then the strength of using more from using both at once. Alpha Androstenol seems to have the same ability to increase LH also btw which is why JV Kohl put it in his scent of eros with getting women to approach you as well, and again is a big buffer and no depression effect. Alpha Androstenol interestingly also activated VN1R1 I believe from that study in the hedione thread. Decanal (Aldehyde C-10) may be a actual pheromone in humans that does the same thing as I mentioned it has the same VN1R1 activation and comes off the body.