From the reviews below, ‘Smiley’ perfume to does sound indeed interesting to try especially considering that it contains PEA, known as the ‘love chemical’ in chocolate.
http://makeupalley.com/product/showreview.asp/ItemID=88405/Smiley/Unlisted_Brand/Fragrances/ (http://makeupalley.com/product/showreview.asp/ItemID=88405/Smiley/Unlisted_Brand/Fragrances/)
by ladiihpnotiiq (http://makeupalley.com/account/profile.asp?id=406142) on 4/9/2007 8:13:00 AM more reviews by ladiihpnotiiq
I read a review on this perfume a few months back and was definitely intrigued by it’s claims and was dying to smell the perfume myself, but like many other products I have read about, I forget about them the next day. Funnily enough, I was browsing through a Sephora on the other side of town and saw a small, simple display of the stuff. I tested it straight away and my god, did I fall in love! It smells, to and on me, very different, fresh, warm, smooth, silky. I can’t really describe what it smells like because I am sure I have smelt nothing like it before. Posaibly fruity, with a hint of spice. It made e feel warm inside and..happy. I then fell even more deeply in love with this when I saw the price - 17 euros for the 30ml EDT! I was deeply dissapointed though, as I had no cash WHATSOEVER on me, and had to catch the train home. I somehow got it into my head that that was the ONLY Sephora in Madrid that had it, as I hadn’t seen the perfume on display in any other Sephora - I din’t think that maybe it had only been released! Anyway, I could still smell the perfume on myself that night and was still totally in love with it. I then checked out my local Sephora a few days later and to my surprise, they had a small Smiley display! I immediately purchased the 30ml EDT, and am still as impressed with it now as I was with it then. The packaging is ultra cute, bright and happy, and a portion of the profits go to charity, not to mention, is does make me, and anyone else I’ve made smell it…SMILE! 
by karinmun (http://makeupalley.com/account/profile.asp?id=288778) on 2/18/2007 5:35:00 AM more reviews by karinmun
The first antidepressant perfume
Smiley perfume does what it promises: it makes you happy!
I discovered this perfume while browsing at the perfume store and I liked its distinctive packaging. The perfume boxes look like pill boxes, the perfume bottle is pill-shaped and the gift set is packaged like a first-aid kit.
I was curious at first when I sprayed it on, and after a few sniffs I realized it really worked! Instantly I was feeling giddy and happy. The salesperson told me about when there was a promotion of Smiley perfume and how they sprayed the perfume in the air and everybody in the store was in such a happy mood because of it.
Smiley is described as a psycho-tonic fragrance, the first antidepressant perfume. The formula contains natural mood elevators like theobromine and phenylethylamine, derived from pure cocoa extract. It’s a fruity yet spicy unisex smell. I’m not very good in describing scents, but I smell a soft citrus fruit and some of it reminds me of Le Feu d’Issey. The fragrance has top notes like bergamot and orange at the opening. Cocoa, praline and curaçao at the heart of the fragrance. The dry-down features patchouli, myrrh and musk.
I absolutely adore the concept, I like it even more that it works! The packaging design is very original, except you’ll have to lay it flat on its side, it can’t stand up straight. But it won’t roll away or anything.
The antidepressant claim is an exaggeration of the uplifting effects of the aromatherapeutic blend of this perfume. I don’t really buy into the mood elevating chemicals, but I do believe in the effects of aromatherapy. I get the same uplifting effects from essential mandarin oil, although I find this fragrance has a stronger effect and more wearable, ofcourse.
Smiley perfume is available as eau de toilette (normal dose), eau de parfum (strong dose), extrait de parfum (maximum dose) and there’s also a skincare/shower/bath range. The price is reasonable as well. I paid 30 euros for a 30ml eau de toilette.
Let me tell ya, I was looking for an uplifting, aromatherapeutic perfume and now I found it!. I highly recommend this for the ones that need an instant pick-me-up.
Look at happy therapy - smiley - le tout premier parfum anti dépresseur (http://www.smileybeauty.com) for more info, store locators or to purchase online.

Ed Shepp's Scent Spectacular: Antidepressant Perfume Smells Like BS (Ed Shepp's Scent Spectacular: Antidepressant Perfume Smells Like BS)
Laurie (http://www.blogger.com/profile/14192900369015156021) said…
U R so wrong about Smiley perfume! I have it and love it and one of my girlfriends & I have just located the additional items we’ve been waiting for…bath gel, deodorant, etc., and are going to order everything. You are wrong. Smiley smells great.
7:37 AM (http://edsheppscentblog.blogspot.com/2006/10/antidepressant-perfume-smells-like-bs.html#c4296950089776570764#c4296950089776570764)
http://www.luxist.com/2006/08/31/smiley-perfume-by-ora-ito/2#comments (http://www.luxist.com/2006/08/31/smiley-perfume-by-ora-ito/2#comments)
“35. It’s real. I discovered it during a trip to Paris. I was at Sephora, and I said to myself “this can’t possibly be true.” I’m from the U.S., so the fact that something was on sale and that these claims were made was unbelieveable. I tried it on and left the store. .. didn’t like the smell much … then, WOW! You might not want to spray this on your co-workers.
For me, it was euphoric. Absolutely amazing. I’ve been using it once or twice a day – after the first time the effect is a “little” less … probably because my brain knows it now. I’ll definitely buy more when I need it – I got the lotion and eau de toilette. I might have to go back to Paris for it if I can’t get it by mail. It is very uplifting, but the effect for me is really nothing like the antidepressants I know. It’s more like an herbal remedy – a little bit like verveine or valerian but better. It’s not an allopathic drug. I’ve been under incredible stress since I started using it (I got robbed leaving France.) and I’m still relatively calm.
Posted at 11:19AM (http://www.luxist.com/2006/08/31/smiley-perfume-by-ora-ito/2#c2580160#c2580160) on Nov 3rd 2006 by Marie”
http://beautyhatchery.blogspot.com/ (http://beautyhatchery.blogspot.com/)
Beauty Chick (April 1, 2007):
“…The print on the bottle says “Psycho-tonic perfume [normal dose] with micro-nutrients to activate happiness.” That intrigued me. Who doesn’t like to be happy? So I spritzed away. I didn’t feel a wave of euphoria, but - I love the scent and can’t stop smelling my wrists. It’s zesty and warm at the same time, thanks to energizing top notes of bergamot and orange, a heart full of “delectable pleasures” of cocoa, praline and curaçao, and a relaxing base of patchouli, myrrh and musk. It is unisex, so everyone can get happy.
Aside from having aromatherapeutic notes, how does Smiley work as ‘happy therapy’? The makers claim that olfactory molecules theobromine (http://www.chm.bris.ac.uk/webprojects2001/millward/theobromine.htm) and phenylethylamine (http://www.chm.bris.ac.uk/webprojects2001/millward/phenylethylamine.htm), both found in chocolate, can have an antidepressant effect. I definitely find chocolate to be a mood-booster, so I can believe it. And having heard that the skin absorbs much of what is applied to it, why couldn’t these beneficial molecules be absorbed and scoot right up to the happy-center of the brain?..”
Smiley & i Profumi di Firenze Fiori del Cielo ~ new fragrances :: Now Smell This (PressHarbor WordPress Hosting - WordPress Hosting for Serious Sites)
On September 14, 2006 SmileyHappyPerson said:
“I bought some Smiley eau de parfum today, i have to
tell you i didnt believe it at first, but i had a spray while walking through Selfridges in Trafford Centre in
Manchester, and i was hooked after 2-3 mins, i felt like the black cloud had been lifted, i have alot of worries going on at the moment, and this perfume, wow i can tell you, i have felt so happy all day, i can also tell you, not once have i fancied chocolate or wanted to eat anything sweet. So with some luck it wwill help me lose weight too, i have to say, it really does make a person feel like they are in love, you know when you first meet someone, you have that honeymoon period where you are totally in love, well that is how this perfume makes you feel. I can happily say, i have not stopped smiling all day, i will be soooo sad if this comes off the market,.
This perfume is lovely, and the bottle is very trendy, it comes in a bright white and yellow box, with a smiley face on it, i recommend this very much.
I am all for something that makes me happy, life
is not for sadness!!!”