I agree fully that excessively high doses are problematic – esp. in the in the very short term that many people judge by “nightly trip reports”]. I feel my own experiences validate that concern: I have long had good reason to suspect that my personal sig is unusually strong in one or more pheros, and I’ve had a few striking OD experiences with certain spray-on pheros.
I also agree that we tread in unexplored territory when it comes to medium- to long- term effects, and that this is a legitimate scientific concern. However, I personally don’t worry too much about that in my own use, until I see research supporting such concern. I think it is perfectly rational to have such concerns but I also strongly doubt that we will see studies confirming or discrediting such concerns in a timeframe that would be meaningful to us as human beings (Will you be in the same phase/station of life in 10-20 years? Will those results still be meaningful to you if/when they come?)
“Normal” is a myth to any one human. Each of us is an individual data point. When I was born, no one dreamt that building on/over very common structurally desirable geologic formations could cut your life short by decades – and it almost never will, but we now know that radioactive xenon gas can accumulate in some solid granite formations, causing a very measurable (but small) number of cancers.
I happen to have built my house over such a formation. I’m not sweating it.
I was finishing medical school when over-the-counter melatonin became completely legally sanctioned in the US as part of an “Alternative Health” reform deriving from the so-callled Health Care Reforms of the early Clinton Administration (I’ll spare you the politics), and it was widely accepted among students, residents and professors that the long term effects of melatonin supplementation was completely unstudied at that time. Yet residents still commonly took melatonin knowing this (as I did, myself – though I took 1/8th of a standard 3mcg tablet, because the studies concerning its efficacy were performed at 200ng vs the common 3mcg=3000ng OTC tablet dose) We judged that melatonin’s yet-observed short term effects were far less concerning than those of conventional sedatives, that our primary exposure would be limited to our training years, and that we would be among to first to know if a cause for concern emerged because it was part of our job to keep abreast of breaking studies.
Well, it’s been 20 years. The full-depth studies still haven’t been undertaken. I stopped taking melatonin, even at 3000/8 ng doses in the late 90s, despite a lifelong history of insomnia – yet I still recommend it to my elderly parents for occassional use, because I still believe it to be safer than the other pharmacological alternatives (my father and grandfather were also physicians; if they take my advice, it’s based on their own knowledge – and the fact that I saved them with diagnoses so tricky that they were written up in major journals)
Likewise, it is my personal judgment that medium term (months/years) exposure to pheromone sprays is likely to be fairly innocuous, even at strikingly high doses. I’m glad that MMDI raised this valid concern, but I don’t sweat it personally. I’m MUCH more concerned with the short-term interpersonal effects. You could easily blow it with “The One You Should Have Been With”, and suffer the consequences.
That’s the way life is. We’re not norms or deviations from the norm. We’re each individual data points --precious snowflakes, if you will-- molded more by such trivia as when we choose to step off the curb [did we look both ways?], a foul mood on a certain evening in a certain bar, or an impulsive fling [where we got caught] than by the parts-per-million health risks of a phero we reasonably judged safe.
So be aware and keep your eyes open. But don’t let it paralyze you. That, too, is risky