During these past few years of wearing pheromones at work–a college campus–I have not found this to be the case. However I don’t think my associates build up a true tolerance. They merely get used to an over used phero signature and stop responding. When I rotate mixes I don’t incorporate radical transformations. Instead, it’s more of a “varations on a theme” type of thing. After all, I’m looking for approiate reactions and enhancement of interactions, not rotations of DIHL, burning lust or fear reactions.
I think an analogy to clothing is apt. One day I wear Lucky jeans whereas the next I don Seven or Kenneth Cole. The observant notice the change–young women–but they’re basically still jeans and appropriate to my persona. Now if I showned up in a Speedo or Tux I would raise eyebrows. A smart rotation of mixes is very similar. You build mixes for results appropriate to the situation and your persona. There are many ways to get there, but it’s nice to take a little different route everyday. And, like different Jeans, the observant notice and respond.